Urgent Public Health Research

As part of the response to the COVID-19 pandemic, LPT has been devoting our R&D resources to help support,  primarily on UPH (Urgent Public Health) Research – research that needs to take place during the emergency phases of the pandemic when infection rates are high. The goal of the NIHR is to gather the necessary clinical and epidemiological evidence that will inform national policy and enable new diagnostics, treatments and vaccines to be developed and tested.

The studies that LPT is currently supporting include:


DIRECT aims to determine whether there are differences in immune responses to COVID-19 infection and vaccination between healthcare workers from different ethnic groups. DIRECT needs to recruit people of all ethnicities but is particularly keen to involve people from ethnic minority groups and those who have previously had confirmed or suspected COVID-19.

You can take part regardless of whether or not you have had a COVID vaccine.

To see details of the study, or to sign up go to https://direct.uk-reach.org/lpt

UK-REACH Title Graphic


The Behavioural Activation in Social IsoLation (BASIL C-19) study aims to test whether a brief remotely-delivered psychological intervention (Behavioural Activation, BA) is effective at preventing or mitigating depression and loneliness in older people with long-term conditions who are socially isolated in relation to Covid-19.

For this study have identified staff to step up to be part of this exciting work, as a BASIL Support Worker for the duration of the Study. Please click on the links below to look at the profile of the people we are looking for, and what the role entails

BASIL C-19 (Person Profile)

BASIL C-19 (Support Worker Role Description)

ISARIC/WHO Clinical Characterisation Protocol for Severe Emerging Infections in the UK (CCP-UK

CCP-UK is a national Urgent Public Health COVID-19 research study backed by the World Health Organisation (WHO) which aims to collect an immense amount of data regarding COVID-19 patient admissions across the NHS.  Initially the study focussed on acute hospital admissions, but later extended to collect detailed information about inpatient admissions of COVID-19 positive patients in all NHS Trusts.

SIREN (SARS-CoV2 Immunity & Reinfection Evaluation)

This national Public Health England study aims to estimate the prevalence of SARS-CoV-2 infection in healthcare workers, to estimate the subsequent incidence of symptomatic and asymptomatic SARS-CoV-2 infection and explore how this varies over time, age, sex, ethnicity and co-morbidities.

Recruitment for this study closed in December 2020, but people may choose to join UK-REACH DIRECT instead. See recruitment poster with the link below:

LPT version SIREN Recruitment poster v1.0 19082020

COVID Oximetry @ home (CO@h): A rapid patient experience study

During the first wave of the COVID-19 pandemic, some patients were not admitted to hospital until they were displaying advanced symptoms of COVID-19. These patients may then have received invasive treatments and/or been admitted to intensive care. Monitoring patients at home may help to reduce these delays and identify patients earlier. In the UK, a healthcare service called COVID Oximetry @home has been nationally rolled out by NHS England. In COVID Oximetry @home, patients receive COVID care at home. As part of this service, patients are given an oximeter and
asked to record their oxygen levels regularly. Patients are monitored and sent for further care if problems arise.

Therefore, this research will focus on exploring patients’ views on the COVID oximetry @ home service, and their experiences of receiving and engaging with COVID oximetry @home.

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