Email lpt.research@nhs.net to find out more about the studies below.

IMID BioResource, Immune-Mediated Inflammatory Diseases

This study aims to recruit 16,000 participants nationally and collect blood/saliva samples and data on patient with IMID conditions.

Immune-Mediated Inflammatory Diseases are a wide group of health conditions which trigger the immune system to fight itself, leading to inflammation. These conditions include Rheumatoid Arthritis, SLE and Psoriasis. IMID Bioresource will help to support research into biomarkers which may be shared between IMID conditions, patient outcomes and links between health, genes and the environment. LPT is working closely with primary care to support recruitment to this study, the local Principal Investigator is Prof. Sudip Ghosh. Further information can be found here: https://bioresource.nihr.ac.uk/centres-programmes/imid-bioresource/

PI: Prof. Sudip Ghosh
Research Delivery Team: Debbie Glancy, Jo McGarr

 

REACH-HFpEF, Heart Failure

LPT's heart failure rehab team is part of this national study evaluating a facilitated home-based rehabilitation intervention in patients with heart failure with preserved ejection fraction.

This study opened in LPT in July 2022, and has 9 participants to date. LPT’s heart failure rehab team is part of this national study evaluating a facilitated home-based rehabilitation intervention in patients with heart failure with preserved ejection fraction. Participants will receive either 12 weeks of a new standardised home-based rehabilitation programme or usual care.

PI: Dr Lizelle Bernhardt
Research Delivery Team: Dr Sarah Baillon, Lynne Hartwell, Jo McGarr, Tom Pringle

 

 

SIT and be FIT, Diabetic Foot Ulcers

This research study aims to help discover the health effects that seated exercise training may have in patients with diabetic foot ulcers

Heart problems are common in patients with a diabetic foot ulcer, and are one of the leading causes of death worldwide. One way by which individuals can improve the function of their heart and improve their blood sugar control is by engaging in regular exercise. Keeping diabetic foot ulcer patients physically active while remaining off their feet is an area of research that is yet to be explored. The main purpose of this study is to see if the efficiency of the heart can be improved through a 12 week seated exercise programme.

PI: Lesley Weaving
Research Delivery Team: Dr Sarah Baillon

 

 

Footwear Fit, Diabetic Foot Ulcers

The main purpose of this study therefore is to assess the average pressure within shoes associated with each recommended footwear fit guideline.

One in five foot ulcers are caused by inappropriate or poorly fitting footwear worn by people with diabetes. There are several recommended guidelines for footwear fit. However, these guidelines have yet to be evaluated to determine which is most effective at reducing in-shoe pressures or temperatures associated with abrasion or movement within footwear. This is important to provide evidence leading ultimately to the standardisation of footwear guidance provided to people with diabetes.

PI: Lesley Weaving
Research Delivery Team: Dr Sarah Baillon

 

 

RAMP Study, Cardiac Rehabilitation

The RAMP study hopes to explore Cardiac Rehabilitation data in Leicester to understand who attends and who has better outcomes after attending rehabilitation

People with cardiac and respiratory conditions can experience poorer quality of life and shorter length of life, compared to people without. Rehabilitation (including exercise and education) can significantly improve these outcomes, but not all patients have the same access to rehabilitation or the same benefits from rehabilitation when they attend. The RAMP Study intends to look at Cardiac Rehabilitation data in Leicester (across LPT and UHL) to better understand who attends (and does not attend) and who has better outcomes (physical health and quality of life) following their attendance.

Chief Investigator: Dr Lizelle Bernhardt

The information on this page is correct as of November 2023.

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